PUSI # | Igoa Oloa | Fa'amatalaga |
CPD100391 | SHP394 | |
CPD100390 | SHP389 (fa'avae fua) | |
CPD3242 | RMC-4550 | RMC-4550 ose malosi ma filifili SHP2 inhibitor. RMC-4550 ua faailoaina o se mea faigaluega maualuga maualuga e suʻesuʻe ai le matafaioi a le SHP2 i le tumo biology, i vitro ma in vivo i rodents. O le SHP2 o se node faʻailoga faʻafesoʻotaʻi ma faʻalavelaveina o le SHP2 e aoga i le tulimataʻiina o suiga uma i luga (RTK-driven) ma lalo (RAS-GTP faʻalagolago) i le ala RAS-MAPK. |