Egelani

Igoa vaila'au:

5-chloro-N-((2S,3R)-4-((3S,4R)-3,4-dihydroxypyrrolidin-1-yl)-3-hydroxy-4-oxo-1-phenylbutan-2-yl)- 1H-indole-2-carboxamide

SMILES Code:

O[C@H](C1)[C@@H](O)CN1C([C@H](O)[C@H](CC2=CC=CC=C2)NC(C3=CC4=C( N3)C=CC(Cl)=C4)=O)=O

InChi Code:

InChI=1S/C23H24ClN3O5/c24-15-6-7-16-14(9-15)10-18(25-16)22(31)26-17(8-13-4-2-1-3- 5-13)21(30)23(32)27-11-19(28)20(29)12-27/h1-7,9-10,17,19-21,25,28-30H,8, 11-12H2,(H,26,31)/t17-,19-,20+,21+/m0/s1

InChi Key:

GVDRRZOORHCTAN-MJUUVYJYSA-N

upu autu:

Egelani; CP-296; CP-368; CP-368,296; CP296; CP 296; CP-368296; CP368296; CP 368296

Solubility:DMSO

Teuina: 

Fa'amatalaga:

Ingliforib, e lauiloa foi o le CP-368296, o se mea fou o le glycogen phosphorylase inhibitor. O le Ingliforib e iai le antihyperglycemic ma le cardioprotective properties. O le Ingliforib e taofia le glycogen phosphorylase, o le enzyme e faʻatapulaʻaina le fua o le glycogenolysis, ma taofia ai le tuʻuina atu o le kulukose-1 phosphate mai se mole glycogen i le ate. O lenei sooupu e taofia foi le glycogen phosphorylase i maso fatu ma e mafai ona puipuia le fatu mai manuʻa ischemic myocardial e ala i le faʻasaoina o mea o le glycogen ma faʻaleleia le faʻaogaina o le glycolytic-oxidative.

Manulauti: glycogen phosphorylase