GDC6036; GDC6036 atropisomers
Fa'amatalaga Oloa
Faailoga o oloa
Tele o le afifi | Avanoa | Tau (USD) |
0.1G | E tele | 870 |
Igoa vaila'au:
2-Propen-1-tasi, 1-[(3S)-4-[7-[6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2- [[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]-
SMILES Code:
C=CC(N1C[C@H](C)N(C2=C3C=C(Cl)C(C4=NC(N)=CC(C)=C4C(F)(F)F)=C(F) )C3=NC(OC[C@H]5N(C)CCC5)=N2)CC1)=O
InChi Code:
InChI=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32), 33)34)15(2)11-20(35)36-2 6)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17)4/h5,11-12,16-17H,1,6- 10,13-14H2,2-4H3,(H2,35,36)/t16-,17-/m0/s1
InChi Key:
ZRBPIAWWRPFDPY-IRXDYDNUSA-N
upu autu:
2417917-17-8;CAS:2417917-17-8;CAS:2417917-17-8;GDC6036 atropisomers; GDC-6036; GDC 6036; GDC6036
Solubility:
Teuina:Mago, pogisa ma i le 0 - 4 C mo taimi pupuu (aso i vaiaso) po'o le -20 C mo taimi uumi (masina i tausaga).
Fa'amatalaga:
O le GDC6036 anti rotation isomer e lua ituaiga o GDC6036 anti rotation isomers. GDC-6036, Fa'aigoaina fo'i o le RG6330, o se fa'atomuaga tu'ugutu, sili ona lelei, ma filifili KRAS G12C inhibitor.
Sini: KRAS G12C