OTS964
Ibicuruzwa birambuye
Ibicuruzwa
Ingano | Kuboneka | Igiciro (USD) |
1g | Mububiko | 1750 |
Ingano nini | Shaka Amagambo | Shaka Amagambo |
Izina ryimiti:
(R) -9- (4- (1- (1)
Kode ya SMILES:
[H] Cl.O = C1NC2 = C (C (C3 = CC = C ([C @@ H] (C) CN (C) C) C = C3) = C (O) C = C2C) C4 = C1SC = C4
InChi Code:
InChI = 1S / C23H24N2O2S.ClH / c1-13-11-18 (26) 19 (16-7-5-15 (6-8-16) 14 (2) 12-25 (3) 4) 20-17- 9-10-28-22 (17) 23 (27) 24-21 (13) 20; / h5-11,14,26H, 12H2,1-4H3, (H, 24,27); 1H / t14-; /m0./s1
InChi Urufunguzo:
YHPWOYBWUWSJDW-UQKRIMTDSA-N
Ijambo ryibanze:
OTS 964, OTS-964, OTS964, 1338545-07-5
Gukemura:Gukemura muri DMSO
Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi)
Ibisobanuro:
OTS964 ni inhibitori ya lymphokine ikora umwicanyi T selile ikomoka kuri protein kinase (TOPK; IC50 = 28 nM). Irahagarika cyane cytokinesis, iganisha kuri apoptose, mubice byinshi bya selile. OTS964 itera apoptose ya kanseri yibihaha ya muntu mumashusho xenografts.
Intego: TOPK