OTS964

OTS964
  • Izina:OTS964
  • Cataloge No.:CPDB0996
  • CAS No.:1338545-07-5
  • Uburemere bwa molekile:392.5
  • Imiti yimiti:C23H24N2O2S
  • Kubushakashatsi bwa siyansi gusa, ntabwo kubarwayi.

    Ibicuruzwa birambuye

    Ibicuruzwa

    Ingano Kuboneka Igiciro (USD)
    1g Mububiko 1750
    Ingano nini Shaka Amagambo Shaka Amagambo

    Izina ryimiti:

    (R) -9- (4- (1- (1)

    Kode ya SMILES:

    [H] Cl.O = C1NC2 = C (C (C3 = CC = C ([C @@ H] (C) CN (C) C) C = C3) = C (O) C = C2C) C4 = C1SC = C4

    InChi Code:

    InChI = 1S / C23H24N2O2S.ClH / c1-13-11-18 (26) 19 (16-7-5-15 (6-8-16) 14 (2) 12-25 (3) 4) 20-17- 9-10-28-22 (17) 23 (27) 24-21 (13) 20; / h5-11,14,26H, 12H2,1-4H3, (H, 24,27); 1H / t14-; /m0./s1

    InChi Urufunguzo:

    YHPWOYBWUWSJDW-UQKRIMTDSA-N

    Ijambo ryibanze:

    OTS 964, OTS-964, OTS964, 1338545-07-5

    Gukemura:Gukemura muri DMSO

    Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi)

    Ibisobanuro:

    OTS964 ni inhibitori ya lymphokine ikora umwicanyi T selile ikomoka kuri protein kinase (TOPK; IC50 = 28 nM). Irahagarika cyane cytokinesis, iganisha kuri apoptose, mubice byinshi bya selile. OTS964 itera apoptose ya kanseri yibihaha ya muntu mumashusho xenografts.

    Intego: TOPK


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