GDC-0326
Ibicuruzwa birambuye
Ibicuruzwa
Ingano | Kuboneka | Igiciro (USD) |
1g | Mububiko | 1800 |
Ingano nini | Shaka Amagambo | Shaka Amagambo |
Izina ryimiti:
(S) -2 - (((2- ] oxazepin-9-yl) oxy) propanamide
Kode ya SMILES:
C [C @ H] (OC1 = CC = C2C3 = NC (C4 = NC = NN4C (C) C) = CN3CCOC2 = C1) C (N) = O
InChi Code:
InChI = 1S / C19H22N6O3 / c1-11 (2) 25-19 (21-10-22-25) 15-9-24-6-7-27-16-8-13 (28-12 (3) 17 ( 20) 26) 4-5-14 (16) 18 (24) 23-15 / h4-5,8-12H, 6-7H2,1-3H3, (H2,20,26) / t12- / m0 / s1
InChi Urufunguzo:
SIKYDKLGPWRPMZ-LBPRGKRZSA-N
Ijambo ryibanze:
GDC-0326, GDC0326, GDC 0326, 1282514-88-8
Gukemura:Gukemura muri DMSO
Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi)
Ibisobanuro:
GDC-0326 ni inhibitor ikomeye kandi ihitamo α-Isoform ya Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). GDC-0326 igera kurwego rwo hejuru cyane rwo guhitamo kurenza izindi kinase. GDC-0326 ifite plasma nkeya CL mubantu. Mu muryango wa PI3 kinase, hari ibyiciro bine I PI3K isoforms (α, β, δ, na γ). Muri iyi isoforms, PI3Kα niyo ikunze guhura na kanseri.
Intego: PI3K