GDC-0326

GDC-0326
  • Izina:GDC-0326
  • Cataloge No.:CPDD3857
  • CAS No.:1282514-88-8
  • Uburemere bwa molekile:382.424
  • Imiti yimiti:C19H22N6O3
  • Kubushakashatsi bwa siyansi gusa, ntabwo kubarwayi.

    Ibicuruzwa birambuye

    Ibicuruzwa

    Ingano Kuboneka Igiciro (USD)
    1g Mububiko 1800
    Ingano nini Shaka Amagambo Shaka Amagambo

    Izina ryimiti:

    (S) -2 - (((2- ] oxazepin-9-yl) oxy) propanamide

    Kode ya SMILES:

    C [C @ H] (OC1 = CC = C2C3 = NC (C4 = NC = NN4C (C) C) = CN3CCOC2 = C1) C (N) = O

    InChi Code:

    InChI = 1S / C19H22N6O3 / c1-11 (2) 25-19 (21-10-22-25) 15-9-24-6-7-27-16-8-13 (28-12 (3) 17 ( 20) 26) 4-5-14 (16) 18 (24) 23-15 / h4-5,8-12H, 6-7H2,1-3H3, (H2,20,26) / t12- / m0 / s1

    InChi Urufunguzo:

    SIKYDKLGPWRPMZ-LBPRGKRZSA-N

    Ijambo ryibanze:

    GDC-0326, GDC0326, GDC 0326, 1282514-88-8

    Gukemura:Gukemura muri DMSO

    Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi)

    Ibisobanuro:

    GDC-0326 ni inhibitor ikomeye kandi ihitamo α-Isoform ya Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). GDC-0326 igera kurwego rwo hejuru cyane rwo guhitamo kurenza izindi kinase. GDC-0326 ifite plasma nkeya CL mubantu. Mu muryango wa PI3 kinase, hari ibyiciro bine I PI3K isoforms (α, β, δ, na γ). Muri iyi isoforms, PI3Kα niyo ikunze guhura na kanseri.

    Intego: PI3K


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