BAY-299
Ibicuruzwa birambuye
Ibicuruzwa
| Ingano | Kuboneka | Igiciro (USD) |
| 100mg | Mububiko | 500 |
| 500mg | Mububiko | 800 |
| 1g | Mububiko | 1200 |
| Ingano nini | Shaka Amagambo | Shaka Amagambo |
Izina ryimiti:
2- (2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl) -6- (3-hydroxypropyl) -1H-benz [de] isoquinoline-1,3 ( 2H) -Dione
Kode ya SMILES:
OCCCC1 = CC = C (C (N2C3 = C (C) C = C (N (C) C (N4C) = O) C4 = C3) = O) C5 = C1C = CC = C5C2 = O
InChi Code:
InChI = 1S / C25H23N3O4 / c1-14-12-20-21 (27 (3) 25 (32) 26 (20) 2) 13-19 (14) 28-23 (30) 17-8-4-7- 16-15 (6-5-11-29) 9-10-18 (22 (16) 17) 24 (28) 31 / h4,7-10,12-13,29H, 5-6,11H2,1- 3H3
InChi Urufunguzo:
OFWWWKWUCDUISA-UHFFFAOYSA-N
Ijambo ryibanze:
BAY-299, BAY 299, BAY299, 2080306-23-4
Gukemura:Gukemura muri DMSO
Ububiko:0 - 4 ° C mugihe gito (iminsi kugeza ibyumweru), cyangwa -20 ° C mugihe kirekire (amezi).
Ibisobanuro:
BAY-299 ninzitizi ikomeye kandi itoranya ya bromodomain na PHD irimo urutoki (BRPF) proteine yumuryango BRD1 (IC50 = 6 nM), izwi kandi nka BRPF2, hamwe na bromodomain ya kabiri yo gutangiza inyandiko TFIID subunits 1 (TAF1 IC50; = 13 nM) .1 BAY-299 ni> guhitamo inshuro 30 hejuru ya BRPF1, BRPF3, BRD9, na ATAD2 kandi ni> inshuro 300 zatoranijwe kuri BRD4.
Intego: BRPF