SJ-01

Dzina la Chemical:

(E) -1-(3-(3,4,5-trimethoxyphenyl)acryloyl) -5,6-dihydropyridin-2(1H)-chimodzi

SMILES Kodi:

O=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O

InChi kodi:

InChI=1S/C17H19NO5/c1-21-13-10-12(11-14(22-2)17(13)23-3)7-8-16(20)18-9-5-4-6- 15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+

InChi Key:

VABYUUZNAVQNPG-BQYQJAHWSA-N

Mawu ofunika:

20069-09-4;CAS:20069-09-4;CAS:20069-09-4;Piperlongumine; Piplatine.

Kusungunuka:Zosungunuka mu DMSO

Posungira:Zouma, zakuda ndi 0 - 4 C kwa nthawi yochepa (masiku mpaka masabata) kapena -20 C kwa nthawi yaitali (miyezi mpaka zaka).

Kufotokozera:

Piperlongumine, yomwe imadziwikanso kuti Piplatine, ndi biologically active alkaloid/amide kuchokera ku tsabola, monga kuchokera ku tsabola wautali (Piper longum L. - Piperaceae). Tsabola wautali ndi imodzi mwa mankhwala omwe amagwiritsidwa ntchito kwambiri mu mankhwala a Ayurvedic, omwe amagwiritsidwa ntchito pochiza matenda ambiri, kuphatikizapo zotupa. Zomwe zanenedwa za pharmacological za piplartine ndi monga cytotoxic, genotoxic, antitumor, antiangiogenic, antimetastatic, antiplatelet aggregation, antinociceptive, anxiolytic, antidepressant, anti-atherosclerotic, antidiabetic, antibacterial, antifungal, leishmanicidal, trypanocistomidal, and schistosomidal activities. Pakati pa zotsatira za mankhwala a piplatine, katundu wake wa anticancer ndi wodalirika kwambiri.

Cholinga: Piperlongumine ndi alkaloid yomwe imalepheretsa kusintha kwa myofibroblasts mwa kuletsa njira yowonetsera erk1/2