Resmetirom
Tsatanetsatane wa Zamalonda
Zolemba Zamalonda
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Dzina la Chemical:
Resmetirom
SMILES Kodi:
N#CC1=NN(C2=CC(Cl)=C(OC(C=C3C(C)C)=NNC3=O)C(Cl)=C2)C(NC1=O)=O
InChi kodi:
InChI=1S/C17H12Cl2N6O4/c1-7(2)9-5-13(22-23-15(9)26)29-14-10(18)3-8(4-11(14)19)25- 17(28)21-16(27)12(6-20)24-25/h3-5,7H,1-2H3,(H,23,26)(H,21,27,28)
InChi Key:
FDBYIYFVSAHJLY-UHFFFAOYSA-N
Mawu ofunika:
MGL-3196; MGL 3196; VIA 3196; VIA-3196; Resmetirom
Kusungunuka:Zosungunuka mu DMSO, osati m'madzi
Posungira:0 - 4 C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 C kwa nthawi yaitali (miyezi)
Kufotokozera:
Resmetirom, yomwe imadziwikanso kuti MGL-3196, ndi yamphamvu komanso yosankha kwambiri ya hormone receptor β agonist m'mayesero achipatala pofuna kuchiza dyslipidemia. Zotsatira zopindulitsa za mahomoni a chithokomiro (TH) pamagulu a lipid makamaka chifukwa cha zochita zake pa chithokomiro cha hormone receptor β (THR-β) m'chiwindi, pamene zotsatira zake, kuphatikizapo zotsatira za mtima, zimayendetsedwa ndi receptor α (THR). -A).
Cholinga: THR-β
