CPD100768 | Fezolinetant | Fezolinetant, yomwe imadziwikanso kuti ESN-364, ndi Neurokinin-3 (NK-3) receptor antagonist yomwe yakonzedwa kuti igwiritsidwe ntchito pa thanzi la amayi, ndipo ikupangidwira matenda okhudzana ndi kugonana monga endometriosis, polycystic ovarian syndrome ndi uterine fibroids. . Fexolinetant imalola kusinthasintha kwa hypothalamic-pituitary gonadal axis ndi kusankha zochita pa mahomoni okhudzana ndi matenda. Wothandizira akuyembekezeka kukhala wolekerera kwambiri kuposa mankhwala omwe amapikisana nawo omwe amayang'ana GnRH (hormone yotulutsa gonadotropin). |