NST-628

Dzina la Chemical:

3-[[3-fluoro-2-(methylsulfamoylamino)pyridin-4-yl]methyl]-7-(3-fluoropyridin-2-yl)oxy-4-methylchromen-2-one

SMILES kodi:

FC1=C(OC2=CC=C(C(C)=C(CC3=C(F)C(NS(NC)(=O)=O)=NC=C3)C(O4)=O)C4= C2)N=CC=C1

InChi kodi:

InChI=1S/C22H18F2N4O5S/c1-12-15-6-5-14(32-21-17(23)4-3-8-27-21)11-18(15)33-22(29 )16(12)10-13-7-9-26-20(19(13)24)28-34(30,31)25-2/h3-9,11,25H,10H2,1-2H3,( H, 26, 28)

InChi Key:

YQSZJOABXRROQR-UHFFFAOYSA-N

Mawu ofunika:

3002056-30-3;CAS:3002056-30-3;CAS:3002056-30-3;NST-628;NST628;NST 628

Kusungunuka: 

Posungira:Zouma, zakuda ndi 0 -4 C kwa nthawi yochepa (masiku mpaka masabata) kapena -20 C kwa nthawi yaitali (miyezi mpaka zaka).

Kufotokozera:

NST-628 ndi MAPK pathway molecular gel yokhala ndi chotchinga chamagazi muubongo, chomwe chingalepheretse RAF phosphorylation ndi MEK activation.

Cholinga: RAF phosphorylation ndi MEK