Luxdegalutamide; ARV-766
Tsatanetsatane wa Zamalonda
Zogulitsa Tags
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Dzina la Chemical:
4-(4-((1-(4-(((1r,3r))-3-(4-cyano-3-methoxyphenoxy) -2,2,4,4-tetramethylcyclobutyl)carbamoyl)phenyl)piperidin-4- yl)methyl)piperazin-1-yl)-N-((S)-2,6-dioxopiperidin-3-yl) -2-fluorobenzamide
SMILES kodi:
CC1(C)[C@H](NC(C2=CC=C(N3CCC(CN4CCN(C5=CC(F))=C(C(N[C@@H]6C(=O)NC(=O) CC6)=O)C=C5)CC4)CC3)C=C2)=O)C(C)(C)[C@H]1OC1=CC(OC)=C(C#N)C=C1
InChi kodi:
InChI=1S/C45H54FN7O6/c1-44(2)42(45(3,4)43(44)59-33-12-8-30(26-47)37(25-33)5 8-5)50-39(55)29-6-9-31(10-7-29)52-18-16-28(17-19-52)27-51-20-22-53(23- 21-51) 32-11-13-34(35(46)24-32)40(56)48-36-14-15-38(54)49-41(36)57/h6-13,24-25,28, 36,42-43H,14-23,27H2,1-5H3,(H,48,56)(H,50,55)(H,49,54,57)/t36-,42-,43-/m0 /s1
InChi Key:
RDPPBRKNBBXPNZ-FMPIRMQTSA-N
Mawu ofunika:
2750830-09-0;CAS:2750830-09-0;CAS:2750830-09-0;ARV766; ma ARV 766; ma ARV-766; GTPL12624; luxdegalutamide
Kusungunuka:
Posungira:Zouma, zakuda ndi 0 - 4 C kwa nthawi yochepa (masiku mpaka masabata) kapena -20 C kwa nthawi yaitali (miyezi mpaka zaka).
Kufotokozera:
Luxdegalutamide (ARV-766) ndi protein hydrolysis yogwira mtima pakamwa yolunjika ku chimeric (PROTAC) yolunjika pa androgen receptor (AR), yomwe imatha kusokoneza zosintha zokhudzana ndi AR.
Zolinga: AR