Ifebemtinib, BI 853520

Dzina la Chemical:

4- [[4- [(2,3-Dihydro-2-methyl-3-oxo-1H-isoindol-4-yl)oxy]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-2-fluoro- 5-methoxy-N-(1-methyl-4-piperidinyl) benzamide

SMILES kodi:

O=C(NC1CCN(C)CC1)C2=CC(OC)=C(NC3=NC=C(C(F)(F)F)C(OC4=CC=CC(CN5C)=C4C5=O)= N3)C=C2F

InChi kodi:

InChI=1S/C28H28F4N6O4/c1-37-9-7-16(8-10-37)34-24(39)17-11-22(41-3)20(12-19(17)29)35- 27-33-13-18(28(30,31)32)25(36-27)42-21-6-4-5-15-14-38(2)26(40)23(15)21/ h4-6,11-13,16H,7-10,14H2,1-3H3,(H,34,39)(H,33,35,36)

InChi Key:

ULMMVBPTWVRPSI-UHFFFAOYSA-N

Mawu ofunika:

1227948-82-4;CAS:1227948-82-4;CAS:1227948-82-4;Ifebemtinib;BI 853520

Kusungunuka:Zosungunuka mu DMSO, osati m'madzi

Posungira:0 - 4 C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 C kwa nthawi yaitali (miyezi).

Kufotokozera:

Ifebemtinib (BI 853520) ndi inhibitor yamphamvu ya focal adhesion kinase (FAK) yokhala ndi zochitika zapakamwa.

Cholinga: FAK Strong Inhibitor