SJ-01

Nomen chemicum:

(E) -1-(3-(3,4,5-trimethoxyphenyl)acryloyl)-5,6-dihydropyridin-2(1H)-one

SMILES Code:

O=C1C=CCCN1C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O

InChi Code:

InChI=1S/C17H19NO5/c1-21-13-10-12 (11-14(22-2)17(13)23-3)7-8-16(20) 188-9-5-4-6- 15(18)19/h4,6-8,10-11H,5,9H2,1-3H3/b8-7+

InChi Key:

VABYUUZNAVQNPG-BQYQJAHWSA-N

Keyword:

20069-09-4；CAS:20069-09-4；CAS：20069-09-4；Piperlongumine; Piplartine.

Solubilitas:Solutum in DMSO

Repono:Arida, obscura et ad 0 - 4 C ad terminum brevem (dies ad septimanas) vel -20 C ad terminum longum (menses ad annos).

Descriptio:

Piperlongumine , etiam Piplartine notum , biologice alkaloideis/inter piperis activum est , ut ex pipere longo ( Piper longum L. - Piperaceae ) . Piper longum est unus ex medicina Ayurvedic celeberrima, quae multos morbos, inclusos tumores, tractabat. Relata pharmacologicae operationes piplartini includunt cytotoxicum, genotoxicum, antitumorem, antiangiogenicum, antimetastaticum, antiplatelem aggregationem, antinociceptivum, anxiolyticum, antidepressum, anti-atheroscleroticum, antidiabeticum, antibacterial, antifungalum, leishmanicidal, trypanocidalum, et operationes schistosos. Inter plures effectus pharmacologicos piplartini, eius proprietas anticancera est praestantissima.

Scopum: Piperlonguminum est alkaloidum, quod transformationem myofibroblastorum vetat inhibendo erk1/2 viam significans