NST-628

Nomen chemicum:

3-[[3-fluoro-2-(methylsulfamoylamino)pyridin-4-yl]methyl]-7-(3-fluoropyridin-2-yl)oxyl-4-methylchromen-2-one

SMILES Code:

FC1=C(OC2=CC=C(C(C)=C(CC3=C(F)C(NS(NC)(=O)=O)=NC=C3)C(O4)=O)C4= C2)N=CC=C1

InChi Code:

InChI=1S/C22H18F2N4O5S/c1-12-156-5-14(32-21-17(23)4-3-8-27-21)11-18(15)33-22(29)16( 12)10-13-7-9-26-20(19(13)24)28-34(30,31)25-2/h3-9,11,25H,10H2,1-2H3,(H,26 ,28)

InChi Key:

YQSZJOABXRROQR-UHFFFAOYSA-N

Keyword:

3002056-30-3；CAS：3002056-30-3；CAS: 3002056-30-3；NST-628；NST628；NST 628

Solubilitas: 

Repono:Arida, obscura et ad 0 -4 C ad terminum brevem (dies ad septimanas) vel -20 C ad terminum longum (menses ad annos).

Descriptio:

NST-628 iter est MAPK gel viae hypotheticae cum obice permeabilitatis sanguinis cerebri, quae phosphorylationem et MEK activationem inhibere potest.

Target: RAF phosphorylation et MEK