Ingliforib
Product Detail
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Nomen chemicum:
5-chloro-N-((2S,3R)-4-((3S,4R)-3,4-dihydroxypyrrolidin-1-yl)-hydroxy-4-oxo-1-phenylbutan-2-yl)- 1H-indole-2-carboxamide
SMILES Code:
O[C@H](C1)[C@@H](O)CN1C([C@H](O)[C@H](CC2=CC=CC=C2)NC(C3=CC4=C( N3)C=CC(Cl)=C4)=O)=O*
InChi Code:
InChI=1S/C23H24ClN3O5/c24-15-6-7-16-14(9-15)10-18(25-16)22(31)26-17(8-13-4-2-1-3- 5-13) 21(30)23(3 2)27-11-19(28)20(29)12-27/h1-7,9-10,17,19-21,25,28-30H,8,11-12H2,(H,26,31 )/t17-,19-,20+,21+/m0/s1
InChi Key:
GVDRRZOORHCTAN-MJUUVYJYSA-N
Keyword:
Ingliforib; CP-296; CP-368; CP-368,296; CP296; CP 296; CP-368296; CP368296; CP 368296
Solubilitas:DMSO
Repono:
Descriptio:
Ingliforib, etiam ut CP-368296, nova glycogen phosphorylase inhibitor est. Ingliforib proprietates antihyperglycemicas et cardioprotectivas habet. Ingliforib inhibet glycogen phosphorylase, enzyme in glycogenolysin emissitivum, quo impeditur emissio glycogeni phosphatae a moleculo in hepate. Hoc agens glycogenum phosphorylasium etiam in musculus cardiacis inhibet et cor ab iniuria ischaemica myocardiali defendat, contentum glycogenum conservans et copulationem glycolytico-oxidative meliori.
Target: glycogen phosphorylase