Acidi chenodeoxycholic

Nomen chemicum:

(R) -4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl ) Acidum pentanoicum

SMILES Code:

C[C@@H]([C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4( [H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O

InChi Code:

InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16(25)12-15(23)13 -20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+ ,20-,22+,23+,24-/m1/s1

InChi Key:

RUDATBOHQWOJDD-BSWAIDMHSA-N

Keyword:

474-25-9，CAS:474-25-9， CAS：474-25-9， Acidum chenodeoxycholicum acidum anthropodeoxycholicum，CCRIS 2195，Chendol，chenicum acidum; Chenix，Chenodeoxycholic acid， Chenodesoxycholic acid，Chenodiol，Gallodesoxycholic acid， NSC 657949， Xenbilox.

Solubilitas:Solutum in DMSO, non in aqua

Repono:Arida, obscura et ad 0 - 4 C ad terminum brevem (dies ad septimanas) vel -20 C ad terminum longum (menses ad annos);

Descriptio:

Chenodiol, quae etiam acidum chenodeoxycholicum et acidum chenocholicum notum est, bilis acidum est. Occurrit substantia alba crystallina in aqua solubilis sed solubilis in alcohole et acido acetico, puncto liquefacto ad 165-167 °C. Salis huius acidi carboxylici chenodeoxycholatae vocantur. Acidum chenodeoxycholicum medico therapio adhibitum est ad fel fel solvendum. Acidum chenodeoxycholicum in curatione xanthomatosis cerebrotendineae adhiberi potest. Comitatus Giaconda biotechnologia Australiae tractationem Hepatitis C infectio temptavit quae acidum chenodeoxycholicum cum bezafibrate coniungit.

Target: receptor nuclei Activated FXR