AMG-510
Detail Product
Tags Product
| Mezinahiya pakêtê | Berdestbûnî | Biha (USD) |
| 1g | ez bêzarim | 1300 |
| 5g | ez bêzarim | 6000 |
| 10g | ez bêzarim | 10500 |
Navê Kîmyayî:
4-((S)-4-acryloyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl )pyrido[2,3-d]pyrimidin-2(1H)-one
Koda SMILES:
O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C (C5=C(O)C=CC=C5F)=N4)=O)CC1
Koda InChi:
InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8- 7-9-22(24)39)34 -29 (19) 38 (30 (41) 35-28) 27-17 (4) 10-11-33-25 (27) 16 (2) 3 / h6-11,14,16,18,39H,1 ,12-13,15H2,2-5H3/t18-/m0/s1
Bişkojka InChi:
NXQKSXLFSAEQCZ-SFHVURJKSA-N
Keyword:
AMG-510; AMG 510; AMG510
Çareserî:
Embarkirinî:
Terîf:
AMG-510 înhîbîtorek kovalent a KRAS G12C ya hêzdar e. AMG-510 bi awayekî bijartî mutant KRAS p.G12C, di asta DNA, RNA an proteîn de, dike hedef, û bi şêwazek hîn nehatiye ronîkirin, rê li ber derbirînê û/an nîşankirina hucreya tumorê bi mutant KRAS p.G12C digire. Ev dibe ku mezinbûna di hucreyên tumor ên KRAS p.G12C de asteng bike
Armanc: KRAS
