Ziftomenib；KO539

jeneng:(S)-4-Metil-5-((4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pirimidin-4-yl)amino)piperidin -1-yl)metil)-1-(2-(4-(metilsulfonil)piperazin-1-yl)propil)-1H-indole-2-karbonitril

No. Katalog:CPD113642

Nomer CAS:2134675-36-6

Bobot molekul:717.87

Formula kimia:C33 H42 F3 N9 O2 S2

Kanggo riset ilmiah mung, ora kanggo pasien.

Kirimi email kanggo kita Ngundhuh minangka PDF

Detail Produk

Tag produk

Ukuran Paket	kasedhiyan	Rega (USD)
0.1G	Ing Simpenan	650
0,5G	Ing Simpenan	970
1G	Ing Simpenan	1350

Jeneng Kimia:

(S)-4-Metil-5-((4-((2-(methylamino)-6-(2,2,2-trifluoroethyl)thieno(2,3-d)pirimidin-4-yl)amino)piperidin -1-yl)metil)-1-(2-(4-(metilsulfonil)piperazin-1-yl)propil)-1H-indole-2-karbonitril

Kode SMILES:

N#CC(N1C[C@@H](N2CCN(S(=O)(C)=O)CC2)C)=CC3=C1C=CC(CN4CCC(NC5=C(C=C(CC(F)) (F)F)S6)C6=NC(NC)=N5)CC4)=C3C

Kode Inchi:

InChI=1S/C33H42F3N9O2S2/c1-21(43-11-13-44(14-12-43)49(4,46)47)19-45-25(18-37)15-27-22(2) 23(5-6-29(27)45)20-42-9-7-24(8-10-42)39-30-28-16-26(17-33(34,35)36)48- 31(28)41-32(38-3)40-30/h5-6,15-16,21,24H,7-14,17,19-20H2,1-4H3,(H2,38,39,40 ,41)/t21-/m0/s1

Kunci InChi:

BGGALFIXXQOTPY-NRFANRHFSA-N

tembung kunci:

2134675-36-6；CAS:2134675-36-6；CAS:2134675-36-6；Ziftomenib; KO539; KO 539; KO-539

Kelarutan:Kanggo ditemtokake

Panyimpenan:Garing, peteng lan ing 0 - 4 C kanggo jangka cendhak (dina nganti minggu) utawa -20 C kanggo jangka panjang (sasi nganti taun).

katrangan:

Ziftomenib (KO-539) minangka inhibitor interaksi MLL menin karo aktivitas lisan.

Target: menin-MLL

Sadurunge: 4,6-dikloro-5-fluoro-2-Metanasulfonil-piriMidin

Sabanjure: N-Metil-5-(piperazin-1-yl)picolinamide hidroklorida