Vardenafil

Jeneng Kimia:

2-(2-etoksi-5-((4-etilpiperazin-1-yl)sulfonil)fenil)-5-metil-7-propil-3,5,6,7-tetrahydro-4H-5l4-imidazo[1, 5-a][1,3,5]triazin-4-siji

Kode SMILES:

O=C(NC(C1=CC(S(=O)(N2CCN(CC)CC2)=O)=CC=C1OCC)=N3)[N]4(C)C3=CN(CCC)C4

Kode Inchi:

InChI=1S/C23H35N6O4S/c1-5-10-27-16-21-24-22(25-23(30)29(21,4)17-27)19-15-18(8-9-20( 19) 33-7-3)34(31,32)28-13-11-26(6-2)12-14-28/h8-9,15-16H,5-7,10-14,17H2,1- 4H3,(H,24,25,30)

Kunci InChi:

UWRWYSQUBZFWPU-UHFFFAOYSA-N

tembung kunci:

Vardenafil, Levitra, Staxyn, Vivanza, BAY 38-9456, BAY-38-9456, BAY38-9456, 224785-90-4

Kelarutan:Larut ing DMSO

Panyimpenan:0 - 4°C kanggo jangka cendhak (dina nganti minggu), utawa -20°C kanggo jangka panjang (sasi)

katrangan:

Vardenafil, uga dikenal minangka BAY 38-9456, minangka inhibitor PDE5 sing digunakake kanggo ngobati disfungsi ereksi. Indikasi lan kontraindikasi Vardenafil padha karo inhibitor PDE5 liyane; fungsi kasebut ana hubungane karo sildenafil sitrat (Viagra) lan tadalafil (Cialis). Bentenipun antarane molekul vardenafil lan sildenafil sitrat yaiku posisi atom nitrogen lan owah-owahan gugus metil cincin piperazine sildenafil menyang gugus etil. Tadalafil sacara struktural beda karo sildenafil lan vardenafil. Wektu efektif Vardenafil sing relatif cendhak bisa dibandhingake nanging luwih suwe tinimbang sildenafil.

Sasaran: PDE5