TAS-120
Detail Produk
Tag produk
| Ukuran Paket | kasedhiyan | Rega (USD) |
Jeneng Kimia:
1-[(3S)-3-[4-amino-3-[2-(3,5-dimethoxyphenyl)ethynyl]-1H-pirazolo[3,4-d]pirimidin-1-yl]-1-pyrrolidinyl] -2-propen-1-siji
Kode SMILES:
C=CC(N1C[C@@H](N2N=C(C#CC3=CC(OC)=CC(OC)=C3)C4=C(N)N=CN=C42)CC1)=O
Kode Inchi:
InChI=1S/C22H22N6O3/c1-4-19(29)27-8-7-15(12-27)28-22-20(21(23)24-13-25-22)18(26-28) 6-5 -14-9-16(30-2)11-17(10-14)31-3/h4,9-11,13,15H,1,7-8,12H2,2-3H3,(H2,23, 24,25)/t15-/m0/s1
Kunci InChi:
KEIPNCCJPRMIAX-HNNXBMFYSA-N
tembung kunci:
TAS-120
Kelarutan:
Panyimpenan:
katrangan:
TAS-120 minangka inhibitor bioavailable lisan saka reseptor faktor pertumbuhan fibroblast (FGFR) kanthi aktivitas antineoplastik potensial. Inhibitor FGFR TAS-120 kanthi selektif lan ora bisa dibatalake ngiket lan nyegah FGFR, sing bisa nyebabake inhibisi jalur transduksi sinyal sing dimediasi FGFR lan proliferasi sel tumor, lan nambah pati sel ing sel tumor sing overexpressing FGFR. FGFR minangka reseptor tyrosine kinase sing penting kanggo proliferasi, diferensiasi lan kaslametan sel tumor lan ekspresi kasebut diatur ing pirang-pirang jinis sel tumor.
Sasaran: FGFR
