NDI-101150

Jeneng Kimia:

(S)-7-((6-((dimethylamino)metil)-5-(tetrahydrofuran-3-yl)piridin-2-yl)amino)-4-(7-fluoroimidazo[1,2-a]piridin- 3-yl)isoindolin-1-siji

Kode SMILES:

O=C1NCC2=C(C3=CN=C4N3C=CC(F)=C4)C=CC(NC5=CC=C([C@@]6([H])COCC6)C(CN(C)C) =N5)=C21

Kode Inchi:

InChI=1S/C27H27FN6O2/c1-33(2)14-22-18(16-8-10-36-15-16)4-6-24(32-22)31-21-5-3-19( 20-12-30-27(35)26(20)2 1)23-13-29-25-11-17(28)7-9-34(23)25/h3-7,9,11,13,16H,8,10,12,14-15H2,1- 2H3,(H,30,35)(H,31,32)/t16-/m1/s1

Kunci InChi:

QOMXZMCZISKNPU-MRXNPFEDSA-N

tembung kunci:

2628486-22-4；CAS:2628486-22-4；CAS:2628486-22-4；NDI-101150; NDI 101150; NDI101150

Kelarutan: 

Panyimpenan:Garing, peteng lan ing 0 -4 C kanggo jangka cendhak (dina nganti minggu) utawa -20 C kanggo jangka panjang (sasi nganti taun).

katrangan:

NDI-101150 minangka inhibitor HPK1 sing kuat lan selektif (hematopoietic progenitor cell kinase 1).

Sasaran: HPK1