Londamocitinib; JAK1-IN-7; AZD4604; JAC34RRR7S

Jeneng Kimia:

(2R)-N-(3-{5-fluoro-2-[2-fluoro-3-(methanesulfonyl)anilino]pirimidin-4-yl}-1H-indol-7-yl)-3-metoxy-2- (4-methylpiperazin-1-yl) propanamida

Kode SMILES:

O=C(NC1=CC=CC2=C1NC=C2C3=NC(NC4=CC=CC(S(=O)(C)=O)=C4F)=NC=C3F)[C@H](N5CCN(C) )CC5)COC

Kode Inchi:

InChI=1S/C28H31F2N7O4S/c1-36-10-12-37(13-11-36)22(16-41-2)27(38)33-21-8-4-6-17-18(14- 31-26(17)21)25-19(29)15-32-28(35-25)34-20-7-5-9-23(24(20)30)42(3,39)40/ h4-9,14-15,22,31H,10-13,16H2,1-3H3,(H,33,38)(H,32,34,35)/t22-/m1/s1

Kunci InChi:

JNUZADQZHYFJGW-JOCHJYFZSA-N

tembung kunci:

2241039-81-4；CAS:2241039-81-4；CAS:2241039-81-4；Londamocitinib；JAK1-IN-7；AZD4604；AZD-4604；JAC34RRR7S

Kelarutan: 

Panyimpenan:Garing, peteng lan ing 0 - 4 C kanggo jangka cendhak (dina nganti minggu) utawa -20 C kanggo jangka panjang (sasi nganti taun).

katrangan:

Londamocitinib (AZD4604) minangka inhibitor JAK1 selektif sing efektif.

Sasaran: JAK1