Lirafugratinib; RLY-4008

Jeneng Kimia:

N-[4-(4-amino-5-{3-fluoro-4-[(4-metilpirimidin-2-yl)oksi]fenil}-7-metil-7H-pirolo[2,3-d]pirimidin- 6-yl)fenil]-2-metilprop-2-enamide

Kode SMILES:

C=C(C)C(NC1=CC=C(C2=C(C3=CC=C(OC4=NC=CC(C)=N4)C(F)=C3)C5=C(N)N= CN=C5N2C)C=C1)=O

Kode Inchi:

InChI=1S/C28H24FN7O2/c1-15(2)27(37)35-19-8-5-17(6-9-19)24-22(23-25(30)32-14-33-26( 23)36(24 )4)18-7-10-21(20(29)13-18)38-28-31-12-11-16(3)34-28/h5-14H,1H2,2-4H3,(H, 35,37)(H2,30,32,33)

Kunci InChi:

XOQVZSSDIQQUGO-UHFFFAOYSA-N

tembung kunci:

2549174-42-5；CAS:2549174-42-5；CAS:2549174-42-5；Lirafugratinib; RLY-4008; RLY 4008; RLY4008

Kelarutan: 

Panyimpenan:Garing, peteng lan ing 0 - 4 C kanggo jangka cendhak (dina nganti minggu) utawa -20 C kanggo jangka panjang (sasi nganti taun).

katrangan:

Lirafugratinib (RLY-4008) minangka inhibitor FGFR2 sing aktif, ora bisa dibatalake, lan selektif banget.

Sasaran: FGFR2