AMG-510
Detail Produk
Tag produk
| Ukuran Paket | kasedhiyan | Rega (USD) |
| 1g | ing saham | 1300 |
| 5g | ing saham | 6000 |
| 10 g | ing saham | 10500 |
Jeneng Kimia:
4-((S)-4-acrylyl-2-methylpiperazin-1-yl)-6-fluoro-7-(2-fluoro-6-hydroxyphenyl)-1-(2-isopropyl-4-methylpyridin-3-yl )pyrido[2,3-d]pirimidin-2(1H)-siji
Kode SMILES:
O=C(C=C)N1C[C@H](C)N(C2=NC(N(C3=C(C)C=CN=C3C(C)C)C4=C2C=C(F)C (C5=C(O)C=CC=C5F)=N4)=O)CC1
Kode Inchi:
InChI=1S/C30H30F2N6O3/c1-6-23(40)36-12-13-37(18(5)15-36)28-19-14-21(32)26(24-20(31)8- 7-9-22(24)39)34 -29(19)38(30(41)35-28)27-17(4)10-11-33-25(27)16(2)3/h6-11,14,16,18,39H,1 ,12-13,15H2,2-5H3/t18-/m0/s1
Kunci InChi:
NXQKSXLFSAEQCZ-SFHVURJKSA-N
tembung kunci:
AMG-510; AMG 510; AMG510
Kelarutan:
Panyimpenan:
katrangan:
AMG-510 minangka inhibitor kovalen KRAS G12C sing kuat. AMG-510 selektif target mutan KRAS p.G12C, ing tingkat DNA, RNA utawa protein, lan nyegah, liwat cara sing durung diterangake, ekspresi lan / utawa sinyal sel tumor liwat mutan KRAS p.G12C. Iki bisa nyandhet wutah ing sel tumor KRAS p.G12C-expressing
Sasaran: KRAS
