Asam Chenodeoxycholic

Jeneng Kimia:

(R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl )asam pentanoat

Kode SMILES:

C[C@@H]([C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4( [H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O

Kode Inchi:

InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15 +,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

Kunci InChi:

RUDATBOHQWOJDD-BSWAIDMHSA-N

tembung kunci:

474-25-9，CAS:474-25-9，CAS:474-25-9，Chenodeoxycholic Acid，Anthropodeoxycholic acid，Anthropodesoxycholic acid，CCRIS 2195，Chendol，Chenic acid; Chenix, Asam Chenodeoxycholic, Asam Chenodesoxycholic, Chenodiol, Asam Gallodesoxycholic, NSC 657949, Xenbilox

Kelarutan:Larut ing DMSO, ora ing banyu

Panyimpenan:Garing, peteng lan ing 0 - 4 C kanggo jangka cendhak (dina nganti minggu) utawa -20 C kanggo jangka panjang (sasi nganti taun)

katrangan:

Chenodiol, uga dikenal minangka Asam Chenodeoxycholic lan asam chenocholic, minangka asam empedu. Iki minangka zat kristal putih sing ora larut ing banyu nanging larut ing alkohol lan asam asetat, kanthi titik lebur ing 165-167 ° C. Uyah saka asam karboksilat iki diarani chenodeoxycholates. Asam Chenodeoxycholic wis digunakake minangka terapi medis kanggo mbubarake watu empedu. Asam Chenodeoxycholic bisa digunakake ing perawatan xanthomatosis cerebrotendineous. Perusahaan bioteknologi Australia Giaconda wis nguji perawatan kanggo infeksi Hepatitis C sing nggabungake asam chenodeoxycholic karo bezafibrate.

Target: Reseptor nuklir aktif FXR