ARS-1323-Alkyne

Jeneng Kimia:

3-((4-(4-acrylylpiperazin-1-yl)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-2-yl)amino)-N-metil-N- (prop-2-yn-1-yl)propanamida

Kode SMILES:

O=C(N(C)CC#C)CCNC1=NC(N2CCN(C(C=C)=O)CC2)=C3C=C(Cl)C(C4=C(O)C=CC=C4F) =C(F)C3=N1

Kode Inchi:

InChI=1S/C28H27ClF2N6O3/c1-4-11-35(3)22(40)9-10-32-28-33-26-17(27(34-28)37-14-12-36(13- 15-37) 21(39)5-2)16-18(29)23(25(26)31)24-19(30)7-6-8-20(24)38/jam1,5-8,16,38H, 2,9-15H2,3H3,(H,32,33,34)

Kunci InChi:

FCCFZQSNDSLLMI-UHFFFAOYSA-N

tembung kunci:

2436544-27-1；CAS:2436544-27-1；CAS:2436544-27-1；ARS-1323-Alkyne; ARS1323-Alkuna; ARS 1323-Alkuna; ARS-1323 Alkuna

Kelarutan:Larut ing DMSO

Panyimpenan:Garing, peteng lan ing 0 - 4 C kanggo jangka cendhak (dina nganti minggu) utawa -20 C kanggo jangka panjang (sasi nganti taun).

katrangan:

ARS-1323-alkyne, inhibitor switch-II pocket (S-IIP).

Target: saku switch-II (S-IIP)