Luxdegalutamide; ARV-766

Aha kemịkalụ:

4- (4- (1- (4- ((1r, 3r)) -3- (4-cyano-3-methoxyphenoxy) -2,2,4,4-tetramethylcyclobutyl) carbamoyl) phenyl) piperidin-4- yl) methyl) piperazin-1-yl)-N-((S) -2,6-dioxopiperidin-3-yl) -2-fluorobenzamide

Koodu Ọchịchọ:

CC1(C)[C@H](NC(C2=CC=C(N3CCC(CN4CCN(C5=CC(F))=C(N[C@H]6C(=O)NC(=O) CC6=O)C=C5)CC4)CC3)C=C2=O)C(C)(C)[C@H]1OC1=CC(OC)=C(C#N)C=C1

Koodu InChi:

InChi=1S/C45H54FN7O6/c1-44(2)42(45(3,4)43(44)59-33-12-8-30(26-47)37(25-33)5 8-5)50-39 (55)29-6-9-31 (10-7-29)52-18-16-28 (17-19-52)27-51-20-22-53(23- 21-51) 32-11-13-34 (35(46)24-32)40(56)48-36-14-15-38(54)49-41(36)57/h6-13,24-25,28, 36,42-43H,14-23,27H2,1-5H3,(H,48,56)(H,50,55)(H,49,54,57)/t36-,42-,43-/m0 /s1

Igodo InChi:

RDPPBRKNBBXPNZ-FMPIRMQTSA-N

Okwu:

2750830-09-0;CAS:2750830-09-0;CAS:2750830-09-0；ARV766; ARV 766; ARV-766; GTPL12624; luxdegalutamide

Solubility: 

Nchekwa:Akọrọ, ọchịchịrị na na 0 - 4 C maka obere oge (ụbọchị ruo izu) ma ọ bụ -20 C maka ogologo oge (ọnwa ruo afọ).

Nkọwa:

Luxdegalutamide (ARV-766) bụ protin hydrolysis ezubere iche maka chimeric (PROTAC) na-arụ ọrụ ọnụ nke na-ezubere onye na-anabata androgen (AR), nke nwere ike weda mutants nguzogide AR.

Ebumnuche: AR