LOXO-305; LY 3527727; Pirtobrutinib

Aha kemịkalụ:

(S) -5-amino-3- (4- ((5-fluoro-2-methoxybenzamido)methyl) phenyl) -1- (1,1,1-trifluoropropan-2-yl) -1H-pyrazole-4- carboxamide

Koodu Ọchịchọ:

O=C(C1=C(N)N([C@@H](C)C(F)(F)F)N=C1C2=CC=C(CNC(C3=CC(F)=CC=C3OC ==O)C=C2)N

Koodu InChi:

InChi=1S/C22H21F4N5O3/c1-11(22(24,25)26)31-19(27)17(20(28)32)18(30-31)13-5-3-12(4-6-) 13)10-29-21(33)15-9-14(23)7-8-16(15)34-2/h3-9,11H,10,27H2,1-2H3,(H2,28,32 ) (H,29,33)/t11-/m0/s1

Igodo InChi:

FWZAWAUZXYCBKZ-NSHDSACASA-N

Okwu:

2101700-15-4;CAS:2101700-15-4;CAS:2101700-15-4;LOXO-305;LOXO 305 b

Solubility: 

Nchekwa:Akọrọ, ọchịchịrị na na 0 - 4 C maka obere oge (ụbọchị ruo izu) ma ọ bụ -20 C maka ogologo oge (ọnwa ruo afọ).

Nkọwa:

Pirtobrutinib (LOXO-305) bụ onye na-ahọrọ nke ukwuu na nke na-abụghị onye na-emechi BTK na-esote ọgbọ nke nwere ike igbochi mgbanwe mgbanwe mgbanwe BTK C481 dị iche iche.

Ebumnuche: BTK