DEL-22379
Nkọwa ngwaahịa
Mkpado ngwaahịa
Nha ngwugwu | Nnweta | Ọnụ ego (USD) |
100mg | Dị na ngwaahịa | 350 |
250mg | Dị na ngwaahịa | 600 |
1g | Dị na ngwaahịa | 1200 |
Nha ndị ọzọ | Nweta Quotes | Nweta Quotes |
Aha kemịkalụ:
(Z) - N- (3- ((5-methoxy-1H-indol-3-yl) methylene) -2-oxoindolin-5-yl) -3- (piperidin-1-yl) propanamide.
Koodu Ọchịchọ:
O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCC5
Koodu InChi:
InChi=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21) 29-26 (22) 32)28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2,1H3,(H,28 ,31) (H,29,32)/b22-13+
Igodo InChi:
INQUULPXCZAKMS-LPYMAVHISA-N
Okwu:
DEL-22379, DEL22379, DEL 22379, 181223-80-3
Solubility:Soluble na DMSO
Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa)
Nkọwa:
DEL-22379 bụ onye nwere ike na nhọrọ ERK Dimerization inhibitor. DEL-22379 na-egbochi ERK Dimerization na-enweghị emetụta ERK phosphorylation, na-egbochi tumorigenesis nke RAS-ERK ụzọ oncogenes. Ihe fọrọ nke nta ka ọ bụrụ 50% nke ọrịa ọjọọ mmadụ na-egosipụta akara RAS-ERK na-achịkwaghị achịkwa; igbochi ya bụ atụmatụ dị mma maka itinye aka na antineoplastic.
Ebumnuche: ERK