DEL-22379

DEL-22379
  • Aha:DEL-22379
  • Nọmba katalọgụ:CPDB3713
  • Nọmba CAS:181223-80-3
  • Arọ Molecular:444.55
  • Usoro kemịkalụ:C26H28N4O3
  • Maka nyocha sayensị naanị, ọ bụghị maka ndị ọrịa.

    Nkọwa ngwaahịa

    Mkpado ngwaahịa

    Nha ngwugwu Nnweta Ọnụ ego (USD)
    100mg Dị na ngwaahịa 350
    250mg Dị na ngwaahịa 600
    1g Dị na ngwaahịa 1200
    Nha ndị ọzọ Nweta Quotes Nweta Quotes

    Aha kemịkalụ:

    (Z) - N- (3- ((5-methoxy-1H-indol-3-yl) methylene) -2-oxoindolin-5-yl) -3- (piperidin-1-yl) propanamide.

    Koodu Ọchịchọ:

    O=C(NC1=CC2=C(NC(/C2=C/C3=CNC4=C3C=C(OC)C=C4)=O)C=C1)CCN5CCCCC5

    Koodu InChi:

    InChi=1S/C26H28N4O3/c1-33-19-6-8-23-20(15-19)17(16-27-23)13-22-21-14-18(5-7-24(21) 29-26 (22) 32)28-25(31)9-12-30-10-3-2-4-11-30/h5-8,13-16,27H,2-4,9-12H2,1H3,(H,28 ,31) (H,29,32)/b22-13+

    Igodo InChi:

    INQUULPXCZAKMS-LPYMAVHISA-N

    Okwu:

    DEL-22379, DEL22379, DEL 22379, 181223-80-3

    Solubility:Soluble na DMSO

    Nchekwa:0 - 4 Celsius C maka obere oge (ụbọchị ruo izu), ma ọ bụ -20 Celsius maka ogologo oge (ọnwa)

    Nkọwa:

    DEL-22379 bụ onye nwere ike na nhọrọ ERK Dimerization inhibitor. DEL-22379 na-egbochi ERK Dimerization na-enweghị emetụta ERK phosphorylation, na-egbochi tumorigenesis nke RAS-ERK ụzọ oncogenes. Ihe fọrọ nke nta ka ọ bụrụ 50% nke ọrịa ọjọọ mmadụ na-egosipụta akara RAS-ERK na-achịkwaghị achịkwa; igbochi ya bụ atụmatụ dị mma maka itinye aka na antineoplastic.

    Ebumnuche: ERK


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