AZD0780;EX-A6975;laroprovstatum; laroprovstat

Aha kemịkalụ:

6 '-( (1S, 3S) -3-( (5- (difluoromethoxy) pyrimidin-2-yl) amino) cyclopentyl) amino) -2H-[1,3'-bipyridin] -2-otu

Koodu Ọchịchọ:

O=C1N(C=CC=C1)C2=CN=C(N[C@@H]3C[C@H](CC3)NC4=NC=C(OC(F)F)C=N4)C= C2

Koodu InChi:

InChi=1S/C20H20F2N6O2/c21-19(22)30-16-11-24-20(25-12-16)27-14-5-4-13(9-14)26-17-7-6- 15 (10 -23-17)28-8-2-1-3-18(28)29/h1-3,6-8,10-14,19H,4-5,9H2,(H,23,26)(H ,24,25,27)/t13-,14-/m0/s1

Igodo InChi:

NCHUWRLOTSAFFN-KBPBESRZSA-N

Okwu:

2455427-91-3;CAS:2455427-91-3;CAS:2455427-91-3；AZD0780; AZD0780; AZD0780; EX-A6975; EX-A 6975; EXA6975; laroprovstatum; laroprovstat

Solubility: 

Nchekwa:Akọrọ, ọchịchịrị na na 0 -4 C maka obere oge (ụbọchị ruo izu) ma ọ bụ -20 C maka ogologo oge (ọnwa ruo afọ).

Nkọwa:

PCSK9-IN-12 bụ ngwakọta heteroaromatic. PCSK9-IN-12 nwere njikọ chiri anya maka PCSK9 nwere uru Kd<200 nM. Enwere ike iji PCSK9-IN-12 mee ihe maka ọmụmụ cholesterol metabolism.

Ebumnuche: PCSK9