Divarasib, GDC 6036

Aha kemịkalụ:

1-((S) -4- (7- ((R) -6-amino-4-methyl-3- (trifluoromethyl) pyridin-2-yl) -6-chloro-8-fluoro-2-(((((( S) -1-methylpyrrolidin-2-yl) methoxy) quinazolin-4-yl) -3-methylpiperazin-1-yl) prop-2-en-1-otu.

Koodu Ọchịchọ:

NC1=N[C@]([C@]2=C(C=C3C(N=C(N=C3N4[C@H](CN(CC4)C(C=C)=O)C)OC[ C@H]5N(CCC5)C=C2F)Cl=C(C(C)=C1)C(F)(F)F

Koodu InChi:

InChi=1S/C29H32ClF4N7O2/c1-5-21(42)40-9-10-41(16(3)13-40)27-18-12-19(30)22(26-23(29(32, 33)34)15 (2)11-20 (35)36-26)24(31)25(18)37-28(38-27)43-14-17-7-6-8-39(17)4/h5,11-12,16-17H ,1,6-10,13-14H2,2-4H3,(H2,35,36)

Igodo InChi:

ZRBPIAWWRPFDPY-UHFFFAOYSA-N

Okwu:

2417987-45-0;CAS:2417987-45-0;CAS：2417987-45-0;Divarasib;GDC 6036

Solubility:SolubilityA ga-ekpebi

Nchekwa:Akọrọ, ọchịchịrị na na 0 - 4 C maka obere oge (ụbọchị ruo izu) ma ọ bụ -20 C maka ogologo oge (ọnwa ruo afọ).

Nkọwa:

Divarasib (GDC-6036) bụ ihe mgbochi KRAS G12C nwere bioavailability ọnụ na nhọrọ nhọrọ.

Ebumnuche: KRAS G12C inhibitor