Sildenafil Sitrat
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Non Chimik:
5-(2-ethoxy-5-((4-methylpiperazin-1-yl)sulfonyl)phenyl)-1-methyl-3-propyl-1,4-dihydro-7H-pyrazolo[4,3-d]pyrimidin- 7-yon sèl 2-hydroxypropane-1,2,3-tricarboxylate
Kòd SMILES:
"CCCC1=NN(C2=C1NC(=NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N4CCN(CC4)C)OCC)CC(C(=O)O )C(CC(=O)O)(C(=O)O)O "
Kòd InChi:
InChI=1S/C22H30N6O4S.C6H8O7/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9- 18(16)32-6-2)33(30,31)28-12-10- 26(3)11-13-28;7-3(8)1-6(13,5(11)12)2-4(9)10/h8-9,14H,5-7,10 -13H2,1-4H3,(H,23,24,29);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
InChi kle:
DEIYFTQMQPDXOT-UHFFFAOYSA-N
Mot:
Sildenafil Citrate;UK 92480-10;UK-92,480-10;Revatio;VIAGRA;171599-83-0;CAS:171599-83-0;CAS:171599-83-0
Solibilite:Soluble nan DMSO
Depo:0 - 4 ° C pou kout tèm (jou a semèn), oswa -20 ° C pou tèm long (mwa)
Deskripsyon:
Sildenafil, Citrate se yon fòm sitrat nan Sildenafil. Sildenafil se yon inibitè selektif PDE5 (kalite 5 cGMP fosfodiesteraz) ki katalize idroliz 3',5'-cyclic guanosine monofosfat (cGMP). Kòm yon inibitè PDE5, Sildenafil yo te rapòte amelyore neuro-, sinapto- ak anjyogenesis nan modèl rat nan konjesyon serebral ak tou yo rapòte yo dwe yon vazodilatatè modere. Sildenafil te montre tou pou anpeche fòmasyon ti ilsè entesten pwovoke endometacin atravè yon mekanis NO / cGMP-depandan.
Sib: PDE5