Quafloxin

Quafloxin
  • Non:Quafloxin
  • Nimewo katalòg:CPD2205
  • Nimewo CAS:865311-47-3
  • Pwa molekilè:604.67
  • Fòmil chimik:C35H33FN6O3
  • Pou rechèch syantifik sèlman, pa pou pasyan yo.

    Pwodwi detay

    Tags pwodwi

    Gwosè pake Disponibilite Pri (USD)

    Non chimik:

    5-fluoro-N-(2-((S)-1-methylpyrrolidin-2-yl)ethyl)-3-oxo-6-((R)-3-(pirazin-2-yl)pyrrolidin-1-yl )-3H-benzo[b]pirido[3,2,1-kl]phenoxazine-2-carboxamide

    Kòd SMILES:

    FC1=C(N2CC[C@@H](C3=CN=CC=N3)C2)C(OC4=C5C=C6C(C=CC=C6)=C4)=C(N5C=C(C(NCC[ C@H]7N(C)CCC7)=O)C8=O)C8=C1

    Kòd InChi:

    InChI=1S/C35H33FN6O3/c1-40-13-4-7-24(40)8-10-39-35(44)26-20-42 -29-15-21-5-2-3-6-22(21)16-30(29)45-34-31(42)25(33(26)43)17-27 (36)32(34)41-14-9-23(19-41)28-18-37-11-12-38-28/h2-3,5-6,11-12 ,15-18,20,23-24H,4,7-10,13-14,19H2,1H3,(H,39,44)/t23-,24+/m1/s1

    InChi kle:

    WOQIDNWTQOYDLF-RPWUZVMVSA-N

    Mot:

    CX 3543; CX-3543; CX 3543; Quarfloxacin

    Solibilite: 

    Depo: 

    Deskripsyon:

    Quarfloxin, konnen tou kòm Quarfloxacin ak CX-3543, se yon dérivés fluoroquinolone ak aktivite antineoplastic. Quarfloxin deranje entèraksyon ant pwoteyin nukleolin ak yon estrikti ADN G-quadruplex nan modèl ADN ribosomal (rDNA), yon entèraksyon kritik pou byogenesis rRNA ki twò eksprime nan selil kansè yo; dezòd nan entèraksyon ADN G-quadruplex sa a: pwoteyin nan byogenesis rRNA aberan ka lakòz anpèchman nan sentèz ribosome ak apoptoz selil timè.

    Sib:


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