Chenodeoxycholic asid

Non chimik:

(R)-4-((3R,5S,7R,8R,9S,10S,13R,14S,17R)-3,7-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenantren-17-yl ) asid pentanoik

Kòd SMILES:

C[C@@H]([C@H]1CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4( [H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C)CCC(O)=O

Kòd InChi:

InChI=1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10- 8-16(25)12-15(23)13 -20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+ ,20-,22+,23+,24-/m1/s1

InChi kle:

RUDATBOHQWOJDD-BSWAIDMHSA-N

Mot:

474-25-9，CAS:474-25-9，CAS:474-25-9，Chenodeoxycholic Acid， Anthropodeoxycholic acid，Anthropodesoxycholic acid，CCRIS 2195，Chendol，chenic acid; Chenix，Chenodeoxycholic asid，Chenodesoxycholic acid，Chenodiol，Gallodesoxycholic acid， NSC 657949， Xenbilox

Solibilite:Soluble nan DMSO, pa nan dlo

Depo:Sèk, nwa ak nan 0 - 4 C pou kout tèm (jou a semèn) oswa -20 C pou tèm long (mwa a ane)

Deskripsyon:

Chenodiol, konnen tou kòm asid Chenodeoxycholic ak asid chenocholic, se yon asid kòlè. Li rive kòm yon sibstans blan cristalline ensolubl nan dlo men idrosolubl nan alkòl ak asid acetic, ak pwen k ap fonn nan 165-167 °C. Sèl asid karboksilik sa a yo rele chenodeoxycholates. Asid chenodeoxycholic te itilize kòm terapi medikal pou fonn kalkil. Asid chenodeoxycholic ka itilize nan tretman xanthomatosis serebrotendineous. Konpayi byoteknoloji Ostralyen Giaconda te teste yon tretman pou enfeksyon epatit C ki konbine asid chenodeoxycholic ak bezafibrat.

Sib: Aktive nikleyè reseptè FXR