BI-3812

Non Chimik:

1-(5-Chloro-4-((8-methoxy-1-methyl-3-(2-(methylamino)-2-oxoethoxy)-2-oxo-1,2-dihydroquinolin-6-yl)amino)pirimidin -2-yl)-N,N-dimethylpiperidine-4-carboxamide

Kòd SMILES:

O=C(C1CCN(C2=NC=C(Cl)C(NC3=CC4=C(N(C)C)C(C(OCC(NC)=O)=C4)=O)C(OC)=C3) =N2)CC1)N(C)C

Kòd InChi:

InChI=1S/C26H32ClN7O5/c1-28-21(35)14-39-20-11-16-10-17(12-19(38-5)22(16)33(4)25(20)37) 30-23-18( 27)13-29-26(31-23)34-8-6-15(7-9-34)24(36)32(2)3/h10-13,15H,6-9,14H2,1- 5H3,(H,28,35)(H,29,30,31)

InChi kle:

XCGYXEVLQIIEJH-UHFFFAOYSA-N

Mot:

BI-3812; BI 3812; BI3812

Solibilite: 

Depo: 

Deskripsyon:

BI-3812 se yon inibitè ki pisan nan entèraksyon an nan domèn BTB/POZ nan BCL6 ak plizyè ko-represè. Li aji pa anpeche fòmasyon konplèks BCL6::Co-repressor.

Sib: BCL6