BAY-299
Pwodwi detay
Tags pwodwi
| Gwosè pake | Disponibilite | Pri (USD) |
| 100 mg | Nan Stock | 500 |
| 500 mg | Nan Stock | 800 |
| 1g | Nan Stock | 1200 |
| Plis gwosè | Jwenn Quotes | Jwenn Quotes |
Non Chimik:
2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl)-6-(3-hydroxypropyl)-1H-benz[de]izoquinoline-1,3( 2H)-dyon
Kòd SMILES:
OCCCC1=CC=C(C(N2C3=C(C)C=C(N(C)C(N4C)=O)C4=C3)=O)C5=C1C=CC=C5C2=O
Kòd InChi:
InChI=1S/C25H23N3O4/c1-14-12-20-21(27(3)25(32)26(20)2)13-19(14)28-23(30)17-8- 4-7-16-15(6-5-11-29)9-10-18(22(16)17)24(28)31/h4,7-10,12-13,29H,5-6, 11H2,1-3H3
InChi kle:
OFWWWKWUCDUISA-UHFFFAOYSA-N
Mot:
BAY-299, BAY 299, BAY299, 2080306-23-4
Solibilite:Soluble nan DMSO
Depo:0 - 4 ° C pou kout tèm (jou a semèn), oswa -20 ° C pou tèm long (mwa).
Deskripsyon:
BAY-299 se yon inibitè ki pisan ak selektif nan bromodomain ak PHD ki gen dwèt (BRPF) pwoteyin fanmi BRD1 (IC50 = 6 nM), ke yo rele tou BRPF2, ak dezyèm bromodomain nan inisyasyon transkripsyon faktè TFIID 1 (TAF1; IC50). = 13 nM).1 BAY-299 se > 30 fwa selektif sou BRPF1, BRPF3, BRD9, ak ATAD2 epi li se > 300 fwa selektif sou BRD4.
Sib: BRPF