BAY-293
Pou rechèch syantifik sèlman, pa pou pasyan yo.
Pwodwi detay
Tags pwodwi
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Non Chimik:
(R)-6,7-dimethoxy-2-methyl-N-(1-(4-(2-((methylamino)methyl)phenyl)thiophen-2-yl)ethyl)quinazolin-4-amine
Kòd SMILES:
C[C@@H](NC1=C2C=C(OC)C(OC)=CC2=NC(C)=N1)C3=CC(C4=CC=CC=C4CNC)=CS3
Kòd InChi:
InChI=1S/C25H28N4O2S/c1-15(24-10-18(14-32-24)19-9-7-6-8-17(19)13-26-3)27-25-20-11- 22( 30-4)23(31-5)12-21(20)28-16(2)29-25/h6-12,14-15,26H,13H2,1-5H3,(H,27,28,29 )/t15-/m1/s1
InChi kle:
WEGLOYDTDILXDA-OAHLLOKOSA-N
Mot:
BAY-293, BAY 293, BAY293
Solibilite:
Depo:
Deskripsyon:
BAY-293 se yon inibitè SOS1 ki pisan ki bloke deklanchman RAS atravè dezòd entèraksyon RAS-SOS1. BAY-293) oaza inibit entèraksyon KRAS-SOS1 ak yon IC50 de 21 nM epi li se yon pwofonde chimik ki gen anpil valè pou envestigasyon nan lavni.
Sib: SOS1 inibitè