Omarigliptin

Lub npe tshuaj:

(2R,3S,5R)-2-(2,5-difluorophenyl)-5-(2-(methylsulfonyl)pyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)tetrahydro-2H -pyran-3-amine

SMILES Code:

N[C@@H]1[C@@H](C2=CC(F)=CC=C2F)OC[C@H](N3CC4=NN(S(=O)(C)=O)C= C4C3)C1

InChi Code:

InChI = 1S/C17H20F2N4O3S/c1-27(24,25)23-7-10-6-22(8-16(10)21-23)12-5-15(20)17(26-9-12) 13-4-11(18)2-3-14(13)19/h2-4,7,12,15,17H,5-6,8-9,20H2,1H3/t12-,15+,17- /m1/s1

InChi Key:

MKMPWKUAHLTIBJ-ISTRZQFTSA-N

Lo lus tseem ceeb:

Omarigliptin, MK-3102, MK3102, Marizev, 1226781-44-7

Solubility:Soluble hauv DMSO

Cia:0 - 4 ° C rau lub sijhawm luv (hnub mus rau lub lis piam), lossis -20 ° C rau lub sijhawm ntev (hli)

Nqe lus piav qhia:

Omarigliptin, tseem hu ua MK-3102, yog lub zog thiab ua haujlwm ntev DPP-4 inhibitor rau kev kho mob ntshav qab zib hom 2 ib zaug ib lim piam. MK-3102 (omarigliptin), tau txheeb xyuas tias muaj zog thiab xaiv dipeptidyl peptidase 4 (DPP-4) inhibitor nrog cov tshuaj pharmacokinetic zoo heev uas tuaj yeem ua rau tib neeg noj ib zaug ib lim piam thiab xaiv los ua tus neeg sib tw kho mob. Omarigliptin tam sim no nyob rau theem 3 kev kho mob.

Hom phiaj: DPP-4