86-21-64556180 ib

Hauv vitro Pharmacokinetic Assay

Peb pab pawg kws kho mob tshwj xeeb hauv kev txhim kho preclinical, DMPK tshuaj ntsuam thiab IND sau npe. Peb tau tsim ib qho kev sib koom ua ke hauv vitro & hauv vivo tshuaj ntsuam tshuab thev naus laus zis hauv kev txhawb nqa kev tshawb nrhiav tshuaj thiab kev txhim kho. Caerulum Pharma muab cov kev pabcuam hloov tau yooj yim thiab tus kheej rau DMPK cov kev daws teeb meem kom tau txais txiaj ntsig zoo thiab muaj txiaj ntsig kom txav koj cov kev tshawb fawb mus tom ntej.

1. Kawm cov khoom siv

Cov khoom me me, cov khoom ntuj tsim, polypeptides.

2. Muaj kev pabcuam

Kev ntsuam xyuas ntshav plasma/cov ntaub so ntswg protein khi

Plasma rau ntshav piv

Lub siab microsomal metabolic stability

Stability nyob rau hauv lub tsheb thiab plasma

Kev txheeb xyuas cov metabolite

CYP tshuaj tiv thaiv phenotyping

CYP inhibition

3. Hauv kev tsim kho

Hepatocyte Induction

Caco-2 Permeability

UGT cov tshuaj tiv thaiv phenotyping


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