CAT # | Khoom npe | Kev piav qhia |
PAB 1573 | TSI-0077 | GDC-0077 yog qhov ncauj muaj PI3K inhibitor uas muaj peev xwm ua haujlwm antineoplastic. |
PIB 1022 | PIB-549 | IPI549 yog lub zog thiab xaiv PI3Kγ Inhibitor nrog IC50 ntawm 16 nM. |
TIAB SA 3857 | TSI-0326 | GDC-0326 yog ib qho muaj zog thiab xaiv inhibitor ntawm α-Isoform ntawm Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). GDC-0326 ua tiav qib siab ntawm kev xaiv ntau dua lwm cov kinases. GDC-0326 muaj plasma CL tsawg hauv tib neeg. |
PAB 0202 | TIAB SA 8186 | AZD8186 yog thiab inhibitor ntawm beta isoform ntawm phosphoinositide-3 kinase (PI3K), uas muaj peev xwm ua haujlwm antineoplastic. |
TIAB SA 1536 | PQR530 | PQR530 yog lub zog muaj zog dual yias-PI3K / mTORC1 / 2 inhibitor. |
TIAB SA 1573 | TSI-0077 | GDC-0077 yog ib qho kev hais lus muaj thiab xaiv PI3K inhibitor (IC50 = 0.038 + 0.003 nM) nrog> 300-fold xaiv dua lwm yam Class I PI3K isoforms. |