Trelagliptin

Lub npe tshuaj:

(R)-2-((6-(3-aminopiperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methyl)-4-fluorobenzonitrile succinate

SMILES Code:

N#CC1=CC=C(F)C=C1CN(C(N2C)=O)C(N3C[C@H](N)CCC3)=CC2=O

InChi Code:

InChI=1S/C18H20FN5O2/c1-22-17(25)8-16(23-6-2-3-15(21)11-23)24(18(22)26)10-13-7-14( 19) 5-4-12(13)9-20/h4-5,7-8,15H,2-3,6,10-11,21H2,1H3/t15-/m1/s1

InChi Key:

IWYJYHUNXVAVAA-OAHLOKOSA-N

Lo lus tseem ceeb:

Trelagliptin, Trelagliptin succinate, SYR-472, Zafatek, 865759-25-7, 1029877-94-8

Solubility:Soluble hauv DMSO

Cia:0 - 4 ° C rau lub sijhawm luv (hnub mus rau lub lis piam), lossis -20 ° C rau lub sijhawm ntev (hli).

Nqe lus piav qhia:

Trelagliptin, tseem hu ua SYR-472, yog ib qho kev ua yeeb yam ntev dipeptidyl peptidase-4 (DPP-4) inhibitor uas tau tsim los ntawm Takeda rau kev kho mob ntshav qab zib hom 2 (T2D). Ib zaug ib lub lim tiam SYR-472 kev kho mob tau tsim kho kev kho mob thiab kev txhim kho tseem ceeb hauv kev tswj glycemic hauv cov neeg mob ntshav qab zib hom 2. Nws tau txais txiaj ntsig zoo thiab tej zaum yuav yog qhov kev xaiv kho tshiab rau cov neeg mob uas muaj tus kab mob no. Trelagliptin (Zafatek (®)) tau pom zoo hauv Nyij Pooj rau kev kho mob ntawm hom 2 mob ntshav qab zib mellitus (T2DM).

Hom phiaj: DPP-4