86-21-64556180 ib

EGFR

CAT # Khoom npe Kev piav qhia
PIB 100230 JBJ-04-125-02 R-isomer
PEB 3232 NTN21277 NTN21277, tseem hu ua Gefitinib-based PROTAC 3 yog VHL-recruiting PROTAC uas induces degradation ntawm EGFR thiab EGFR mutants nrog DC50 ntawm 11.7 nM thiab 22.3 nM rau HCC827 cell (Exon 19 del5).
TIAB SA 3615 Nazartinib; EGF816; NWS-816 Nazartinib, tseem hu ua EGF816 thiab NVS-816, yog ib qho kev hais lus muaj, irreversible, thib peb tiam, mutant-selective epidermal growth factor receptor (EGFR) inhibitor, muaj peev xwm ua haujlwm antineoplastic.
wb 0934 TSI-045 EAI045 yog lub zog thiab xaiv EGFR inhbitor. EAI045 lub hom phiaj xaiv cov tshuaj tiv thaiv EGFR mutants tab sis cia cov tsiaj qus receptors. EAI045 inhibits L858R / T790M-mutant EGFR nrog qis-nanomolar potency hauv biochemical ntsuam xyuas.
PAB 0101 Poziotinib Cov qauv uas muaj poziotinib tab tom tshawb nrhiav hauv kev sim tshuaj kho mob EGFR-mutant ntsws adenocarcinoma.
PAB 0137 Osimertinib Mesylate Osimertinib, tseem hu ua mereletinib thiab AZD-9291, yog ib tiam thib peb EGFR inhibitor, tau pom cov lus cog tseg hauv kev tshawb fawb ua ntej thiab muab kev cia siab rau cov neeg mob uas muaj mob qog noj ntshav siab uas tau ua rau cov EGFR inhibitors uas twb muaj lawm.
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