TSI-901
Product Detail
Khoom cim npe
Pob Loj | Muaj | Nqe (USD) |
100 mg | Hauv Tshuag | 500 |
500 mg | Hauv Tshuag | 800 |
1g | Hauv Tshuag | 1200 |
Ntau qhov ntau thiab tsawg | Tau txais Quotes | Tau txais Quotes |
Lub npe tshuaj:
5-[(2,4-Dimethoxy-1-naphthalenyl)methylene]dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione
SMILES Code:
O=C(/C(C(N1)=O)=CC2=C3C=CC=CC3=C(OC)C=C2OC)NC1=S
InChi Code:
InChI = 1S/C17H14N2O4S/c1-22-13-8-14(23-2)11(9-5-3-4-6-10(9)13)7-12-15(20)18-17( 24) 19-16(12)21/h3-8H,1-2H3,(H2,18,19,20,21,24)
InChi Key:
JHOPCCOYRKEHQU-UHFFFAOYSA-N
Lo lus tseem ceeb:
IT-901, IB 901, IT 901, 1584121-99-2
Solubility:Soluble hauv DMSO
Cia:0 - 4 ° C rau lub sijhawm luv (hnub mus rau lub lis piam), lossis -20 ° C rau lub sijhawm ntev (hli).
Nqe lus piav qhia:
"IT-901 yog ib qho c-Rel Inhibitor Uas Mediates Anticancer Properties hauv Hematologic Malignancies los ntawm Blocking NF-κB-Controlled Oxidative Stress Responses. IT-901 potently inhibits NF-κB subunit c-Rel. IT-901 suppressed graft-versus- Tus tswv tsev kab mob thaum khaws cia graft-piv rau-lymphoma kev ua si thaum lub sij hawm hloov pauv hloov pauv hloov pauv ntxiv ntawm IT-901 rau kev kho mob ntawm tib neeg B-cell lymphoma qhia cov tshuaj tiv thaiv hauv vitro thiab hauv vivo yam tsis muaj kev txwv rau NF-κB-dependent lymphoma IT-. 901 tsis tau tshem tawm cov qib ntawm cov pa oxygen reactive nyob rau hauv ib txwm leukocytes, qhia txog nws cov kab mob kheesxaws IT-901 yog cov tshuaj kho tshiab los kho cov qog nqaij hlav hauv tib neeg thiab kho cov kab mob qog noj ntshav-tiv thaiv tus tswv tsev.
Hom phiaj: NF-kB