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TSI-901

TSI-901
  • Lub npe:TSI-901
  • Catalog No.:TIAB SA 1661
  • CAS Nr:.1584121-99-2
  • Molecular Luj:342.369 ib
  • Tshuaj Formula:C17H14N2O4S
  • Rau kev tshawb fawb tshawb fawb nkaus xwb, tsis yog rau cov neeg mob.

    Product Detail

    Khoom cim npe

    Pob Loj Muaj Nqe (USD)
    100 mg Hauv Tshuag 500
    500 mg Hauv Tshuag 800
    1g Hauv Tshuag 1200
    Ntau qhov ntau thiab tsawg Tau txais Quotes Tau txais Quotes

    Lub npe tshuaj:

    5-[(2,4-Dimethoxy-1-naphthalenyl)methylene]dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione

    SMILES Code:

    O=C(/C(C(N1)=O)=CC2=C3C=CC=CC3=C(OC)C=C2OC)NC1=S

    InChi Code:

    InChI = 1S/C17H14N2O4S/c1-22-13-8-14(23-2)11(9-5-3-4-6-10(9)13)7-12-15(20)18-17( 24) 19-16(12)21/h3-8H,1-2H3,(H2,18,19,20,21,24)

    InChi Key:

    JHOPCCOYRKEHQU-UHFFFAOYSA-N

    Lo lus tseem ceeb:

    IT-901, IB 901, IT 901, 1584121-99-2

    Solubility:Soluble hauv DMSO

    Cia:0 - 4 ° C rau lub sijhawm luv (hnub mus rau lub lis piam), lossis -20 ° C rau lub sijhawm ntev (hli).

    Nqe lus piav qhia:

    "IT-901 yog ib qho c-Rel Inhibitor Uas Mediates Anticancer Properties hauv Hematologic Malignancies los ntawm Blocking NF-κB-Controlled Oxidative Stress Responses. IT-901 potently inhibits NF-κB subunit c-Rel. IT-901 suppressed graft-versus- Tus tswv tsev kab mob thaum khaws cia graft-piv rau-lymphoma kev ua si thaum lub sij hawm hloov pauv hloov pauv hloov pauv ntxiv ntawm IT-901 rau kev kho mob ntawm tib neeg B-cell lymphoma qhia cov tshuaj tiv thaiv hauv vitro thiab hauv vivo yam tsis muaj kev txwv rau NF-κB-dependent lymphoma IT-. 901 tsis tau tshem tawm cov qib ntawm cov pa oxygen reactive nyob rau hauv ib txwm leukocytes, qhia txog nws cov kab mob kheesxaws IT-901 yog cov tshuaj kho tshiab los kho cov qog nqaij hlav hauv tib neeg thiab kho cov kab mob qog noj ntshav-tiv thaiv tus tswv tsev.

    Hom phiaj: NF-kB


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