MDK7526 HCl

Inoa Kimia:

(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

SMILES Code:

O=C([C@H]1N(C([C@@H](N)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C (C3=C(C)N=CS3)C=C2.[H]Cl

Code InChi:

InChI=1S/C22H30N4O3S.ClH/c1-13-18(30-12-25-13)15-7-5-14(6-8-15)10-24-20(28)17-9-16( 27)11-26(17)21(29)19(23)22(2,3)4;/h5-8,12,16-17,19,27H,9-11,23H2,1-4H3,( H,24,28);1H/t16-,17+,19-;/m1./s1

Ki InChi:

JYRTWGCWUBURGU-MSSRUXLCSA-N

Hua'ōlelo:

MDK7526 HCl, Mea hoʻohaʻahaʻa protein 1 hydrochloride, MDK7526, MDK-7526, MDK 7526, 1448189-80-7

Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO

Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina).

wehewehe:

MDK7526, i ʻike ʻia ʻo VHL Ligand 1; ʻO ka protein degrader 1, he mea hoʻohaʻahaʻa ikaika a koho. Loaʻa iā MDK7526 CAS #1448297-52-6, aia kāna paʻakai HCl CAS #1448189-80-7. Hiki i ka MDK7526 ke kūpono no ka hoʻohaʻahaʻa ʻia ʻana o ka mea hoʻokipa androgen. Hoʻopaʻa ka MDK7526 i ka receptor androgen e like me ka hoʻokomo ʻana o ka androgen ma kahi kokoke i ka ligase ubiquitin e hoʻokō i ka degrdn. (a me ka inhibition) o ka mea hoʻokipa androgen.

Pahuhopu: Androgen Receptor