AZD4547

Inoa Kimia:

N-(5-(3,5-dimethoxyphenethyl)-1H-pyrazol-3-yl)-4-((3S,5R)-3,5-dimethylpiperazin-1-yl)benzamide

SMILES Code:

O=C(NC1=NNC(CCC2=CC(OC)=CC(OC)=C2)=C1)C3=CC=C(N4C[C@H](C)N[C@H](C)C4 )C=C3

Code InChi:

InChI=1S/C26H33N5O3/c1-17-15-31(16-18(2)27-17)22-9-6-20(7-10-22)26(32)28-25-13-21( 29-30-25)8-5 -19-11-23(33-3)14-24(12-19)34-4/h6-7,9-14,17-18,27H,5,8,15-16H2,1-4H3,( H2,28,29,30,32)/t17-,18+

Ki InChi:

VRQMAABPASPXMW-HDICACEKSA-N

Hua'ōlelo:

AZD4547, AZD-4547, AZD 4547, 1035270-39-3

Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO

Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina)

wehewehe:

ʻO AZD 4547 he mea hoʻopaneʻe koho o ka fibroblast growth factor receptor (FGFR) tyrosine kinase me nā koina IC50 o 0.2, 2.5, a me 1.8 nM no FGFR1, 2, a me 3.

Pahuhopu: FGFR