CAT # | Sunan samfur | Bayani |
Saukewa: CPD101235 | DIABZI STING agonist-1 trihydrochloride | diABZI STING agonist-1 (trihydrochloride) wani zaɓi ne na agonist mai karɓa na interferon genes (STING), tare da EC50s na 130, 186 nM don mutum da linzamin kwamfuta, bi da bi. |
Saukewa: CPD101234 | diABZI STING agonist-1 (Tautomerism) | diABZI STING agonist-1 Tautomerism (compound 3) wani zaɓi ne mai zaɓaɓɓen agonist mai karɓa na ƙwayoyin cuta na interferon (STING), tare da EC50s na 130, 186 nM don ɗan adam da linzamin kwamfuta, bi da bi. |
Saukewa: CPD101233 | diABZI STING agonist-1 | diABZI STING agonist-1 zaɓi ne mai zaɓaɓɓen agonist mai karɓa na ƙwayoyin interferon (STING), tare da EC50s na 130, 186 nM don ɗan adam da linzamin kwamfuta, bi da bi. |
Saukewa: CPD101232 | STING agonist-4 | STING agonist-4 shine mai kara kuzari na Interferon Genes (STING) agonist mai karɓa tare da tabbataccen inhibitory akai (IC50) na 20 nM. STING agonist-4 wani abu ne na amidobenzimidazole (ABZI) da ke da alaƙa guda biyu don ƙirƙirar ABZI mai alaƙa (diABZIs) tare da haɓaka haɓakawa zuwa STING da aikin salula. |
Saukewa: CPD101231 | STING agonist-3 | STING agonist-3, wanda aka samo daga lamban kira WO2017175147A1 (misali 10), zaɓi ne kuma mara-nucleotide ƙananan ƙwayoyin STING agonist tare da pEC50 da pIC50 na 7.5 da 9.5, bi da bi. STING agonist-3 yana da tasirin anti-tumor mai dorewa da babban yuwuwar inganta maganin cutar kansa |