STING agonist-3
Cikakken Bayani
Tags samfurin
Girman Kunshin | samuwa | Farashin (USD) |
Sunan Sinadari:
(E) -1- (4- (5-carbamoyl-2-- (1-ethyl-3-methyl-1H-pyrazole-5-carboxamido)-1H-benzo [d] imidazol-1-yl) amma-2- a-1- yl) -2- (1-ethyl-3-methyl-1H-pyrazole-5-carboxamido) -7- (3-hydroxypropoxy) -1H-benzo [d] imidazole-5-carboxamide
Lambar SMILES:
O=C(N)C1=CC=C(N(C(NC(C2=CC(C)=NN2CC)=O)=N3)C/C=C/CN4C5=C(N=C4NC(C6=CC) (C)=NN6CC)=O)C=C(C(N)=O)C=C5OCCCO)C3=C1
Lambar InChi:
InChi=1S/C37H42N12O6/c1-5-48-28(16-21(3)44-48)34(53)42-36-40-25-18-23(3) 2 (38)51)10-11-27 (25)46 (36)12-7-8-13-47-31-26 15-9-14-50)41-37(47)43-35(54)29-17-22 (4)45-49(29)6-2/h7-8,10-11,16-20, 50 H,5-6,9,12-15H2,1-4H3,(H2,38,51)(H2,39,52)(H,40,42,53)(H,41,43,54)/b8 -7+
InChi Key:
VHCDRDBBENBVEK-BQYQJAHWSA-N
Mabuɗin kalma:
Solubility:
Ajiya:
Bayani:
STING agonist-3, wanda aka samo daga lamban kira WO2017175147A1 (misali 10), zaɓi ne kuma mara-nucleotide ƙananan ƙwayoyin STING agonist tare da pEC50 da pIC50 na 7.5 da 9.5, bi da bi. STING agonist-3 yana da tasirin anti-tumor mai dorewa da babban yuwuwar inganta maganin cutar kansa
Manufar: STING