DIABZI STING agonist-1 trihydrochloride

Sunan Sinadari:

(E) -1- (4- (5-carbamoyl-2-- (1-ethyl-3-methyl-1H-pyrazole-5-carboxamido) -7- (3-morpholinopropoxy) -1H-benzo [d] imidazole -1-yl)amma-2-en-1-yl)-2- (1-ethyl-3-methyl-1H-pyrazole-5-carboxamido) -7-methoxy-1H-benzo[d] imidazole-5- carboxamide trihydrochloride

Lambar SMILES:

O=C(N)C1=CC(N=C(NC(C2=CC(C)=NN2CC)=O)N3C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O) =NC6=C4C(OCCCN7CCOCC7)=CC(C(N)=O)=C6=C3C(OC)=C1.Cl.Cl.Cl

Lambar InChi:

CKESNWHACHILIV-BILRHTGOSA-N

InChi Key:

InChi=1S/C42H51N13O7.3ClH/c1-6-54-31(19-25(3)49-54)39(58)47-41-45-29-21-27(37(4) 3)56)23-33 (60-5)35 (29)52 (41)12-8-9-13-53-36-30 (46-42 (53)48-40 (59)32-20- 26 (4) 50- 55 (32)7-2)22-28 (38 (44)57)24-34 (36)62-16-10-11-51-14-17-61-18-15-51;;/h8 -9,19-2 4H,6-7,10-18H2,1-5H3,(H2,43,56)(H2,44,57)(H,45,47,58)(H,46,48,59);3*1H /b9-8+;;

Mabuɗin kalma:

Solubility: 

Ajiya: 

Bayani:

diABZI STING agonist-1 (trihydrochloride) wani zaɓi ne na agonist mai karɓa na interferon genes (STING), tare da EC50s na 130, 186 nM don mutum da linzamin kwamfuta, bi da bi.

Manufar: STING