Saukewa: PCO371

Saukewa: PCO371
  • Suna:Saukewa: PCO371
  • Catalog No.:Saukewa: CPD2050
  • Lambar CAS:1613373-33-3
  • Nauyin Kwayoyin Halitta:635.20
  • Tsarin Sinadarai:Saukewa: C29H32F3N5O6S
  • Don binciken kimiyya kawai, ba ga marasa lafiya ba.

    Cikakken Bayani

    Tags samfurin

    Girman Kunshin samuwa Farashin (USD)

    Sunan Sinadari:

    1- (3,5-dimethyl-4- (2-(4-oxo-2-- (4- (trifluoromethoxy) phenyl)) -1,3,8-triazaspiro [4.5] dec-1-en-8-yl sulfonyl) ethyl) phenyl) -5,5-dimethylimidazolidine-2,4-dione.

    Lambar SMILES:

    O=C1NC(C(C)(C)N1C2=CC(C)=C(CCS(=O)(N(CC3)CCC3(N=C(C4=CC)=C(OC(F)(F)F)) )C=C4)N5)C5=O)=O)C(C)=C2)=O

    Lambar InChi:

    InChi=1S/C29H32F3N5O6S/c1-17-15-20(37-26(40)34-24(38)27(37,3)4)16-18(2)22(17)9-14-44 41,42) 36-12-10-28 (11-13-36)25 (39) 33-23 (35-28) 19-5-7-21 (8-6-19) 43-29 (30, 31)32/h5-8,15-16H,9-14H2,1-4H3,(H,33,35,39)(H,34,38,40)

    InChi Key:

    LDZJFVOUPUFOHX-UHFFFAOYSA-N

    Mabuɗin kalma:

    PCO371; PCO-371; Farashin 371

    Solubility: 

    Ajiya: 

    Bayani:

    PCO371 mai ƙarfi ne kuma mai zaɓin PTHR1 agonist don maganin hypoparathyroidism. Gudanar da baka na PCO371 zuwa berayen osteopenic yana haifar da karuwa mai yawa a cikin jujjuyawar kashi tare da ƙayyadaddun haɓakar ƙasusuwan kashi. A cikin berayen hypocalcemic, PCO371 yana dawo da matakan sinadarai na sinadarai ba tare da haɓaka calcium na fitsari ba, kuma tare da ƙarfi da tasiri mai dorewa fiye da allurar PTH.

    Saukewa: PTHR1


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