Saukewa: NST-628

Sunan Sinadari:

3-[3-fluoro-2- (methylsulfamoylamino) pyridin-4-yl] methyl] -7- (3-fluoropyridin-2-yl) oxy-4-methylchromen-2-one

Lambar SMILES:

FC1=C(OC2=CC=C(C(C)=C(CC3=C(F)C(NS(NC)=O=O)=NC=C3)C(O4)=O)C4= C2)N=CC=C1

Lambar InChi:

InChi=1S/C22H18F2N4O5S/c1-12-15-6-5-14(32-21-17(23)4-3-8-27-21)11-18(15)33-22(29) )16(12)10-13-7-9-26-20(19(13)24)28-34(30,31)25-2/h3-9,11,25H,10H2,1-2H3,( H, 26,28)

InChi Key:

YQSZJOABXRROQR-UHFFFAOYSA-N

Mabuɗin kalma:

3002056-30-3;CAS:3002056-30-3;CAS:3002056-30-3;NST-628

Solubility: 

Ajiya:Dry, duhu kuma a 0 -4 C na gajeren lokaci (kwanaki zuwa makonni) ko -20 C na dogon lokaci (watanni zuwa shekaru).

Bayani:

NST-628 shine hanyar MAPK kwayoyin gel tare da shingen shinge na jini-kwakwalwa, wanda zai iya hana RAF phosphorylation da kunna MEK.

Manufar: RAF phosphorylation da MEK